Grant's micaelamys is endemic to the Karoo regions of South Africa, where it occurs among rocks in arid landscapes.
The fur on its underside is never pure white; it is usually grey or greyish. This helps distinguish it from the related Namaqua rock mouse.
Field information about what it eats and how it breeds is not sufficient for a detailed account of its daily life.
An extinction-risk assessment has not been added yet.