Franklin's ground squirrel prefers tall grass where prairie meets woodland and digs underground burrows. It eats both plant and animal foods. In Missouri, populations have declined with habitat loss and fragmentation.
Its coat is brownish gray with black speckling and a yellowish cast to the rump. It has rounded ears and a shorter, less bushy tail than some other squirrels.
It is active by day and digs burrows in brushy banks or draws. It eats seeds, fruits, roots, and green vegetation as well as insects and small animals.
An extinction-risk assessment has not been added yet.