The hispid pocket mouse has an olive-buff back and a pale underside. It stores food in grassland burrows and mainly eats seeds.
At the Colorado cropland site, Hispid Pocket Mouse capture rate was significantly higher than at the shortgrass-prairie site. It was among the indicators of the agricultural site; samples with the species had an estimated 85.1% probability of belonging to the cropland group.
It digs burrows with several entrances, which may be plugged during the day, and uses them to store food. Seeds are its main food, though it also eats insects.
The back has olive-buff fur and the belly is lighter. Its hind limbs are heavier than its forelimbs, and the soles of its hind feet are hairless.
An extinction-risk assessment has not been added yet.