The Yellow-rumped Leaf-eared Mouse is recorded from rocky sites in the Andes and Patagonia. It has large ears and a long tail, while fur and diet vary across regions.
Its tail is nearly as long as its body, and its ears are large. Fur is denser at high elevations and in harsh climates.
It is terrestrial and nocturnal. Food varies by region: some populations eat mostly leaves and other plants, while insects make up more of the diet in others.
An extinction-risk assessment has not been added yet.