The Zacatecan harvest mouse has a reddish-brown back and a relatively long tail. In Jalisco, it is recorded in high temperate areas.
The back is reddish brown and the underside is dark buff to cinnamon. The tail is usually more than 116% of head-and-body length, according to the Jalisco guide.
In Jalisco, it is recorded in temperate highlands above 1,800 m, from the north of the state south to the Sierra Volcán-Nevado de Colima.
An extinction-risk assessment has not been added yet.