Azara's Akodont lives in grasslands and wetland vegetation, and may change the sheltered sites it uses with the seasons.
Its soft dorsal fur is olive-brown, while the underside is yellowish white. The shoulders and nose are reddish brown, with a faint eye ring.
In the low Delta of Buenos Aires, mice favored temporarily flooded low ground in winter and higher roadsides along ditches in summer and autumn. Herb cover provides shelter from predators.
An extinction-risk assessment has not been added yet.