Akodon polopi is a small rodent described from the Sierras Grandes of central Argentina. It has dense, soft fur and a buff-brown back flecked with black, and has been recorded in highland grassland.
The original description notes dense, soft fur and a buff-brown back lightly flecked with black hairs.
Collection localities in the Sierras Grandes included grasslands dominated by Festuca and Stipa, and rocky grassland with Paspalum and Poa.
An extinction-risk assessment has not been added yet.