The type specimen of Clyde Jones's Myotis came from near-mature lowland tropical forest on an island in Suriname's Coppename River. A 2025 taxonomic comparison describes long, dark-brown dorsal fur, yellowish-brown ventral fur and a bare upper surface of the tail membrane.
In the 2025 comparison, its dorsal fur is longer and darker brown than that of the newly described comparison species; its ventral fur is yellowish brown, and the upper surface of the tail membrane is bare.
The type specimen was captured in a net below large riverside trees in near-mature lowland tropical forest on an island near Raleigh Falls in the Coppename River. The account describes little understory.
An extinction-risk assessment has not been added yet.