The Greater White-toothed Shrew occurs throughout mainland Portugal. Its back changes from gray in winter to reddish brown in summer. It uses open places, shrub-rich woodland edges, gardens and farmland, and is mostly nocturnal but also active by day.
Head and body are about 5–8.5 cm long. The species has white teeth, tiny eyes, rounded ears, a prominent snout, and long pale whiskers. The back is gray in winter and reddish brown in summer; the underside is paler and the tail has short hairs.
It is mostly nocturnal but can be active by day, with periods of rest. It favors open places and forest edges with shrub cover and also occurs in gardens, orchards, farmland, and near rural homes. The account records it throughout mainland Portugal, inland and coastal.
An extinction-risk assessment has not been added yet.