The Zacatecas Shrew is a Mexican shrew. Mexican records describe a dark-brown back, a belly with blond-tipped hairs, and a two-toned tail.
The described specimens had medium to dark-brown dorsal fur, blond-tipped ventral hairs, and a tail with two distinct color zones.
It is recorded from moist, high-elevation pine and pine-oak forests, including wet oak leaf litter. Lactating females were collected in July and August.
In Mexico, it has been recorded as prey of the garter snake Thamnophis elegans.
Guard hairs on the hips and rump project 1.2–1.4 mm beyond the dorsal coat.
An extinction-risk assessment has not been added yet.