The Cape serotine sometimes roosts in the roofs of houses and buildings. Records span arid semi-desert, montane grassland, forest and savanna; it forages at medium height along cluttered edges.
Compared with the related Laephotis kirinyaga, its skull profile is flatter.
It mainly forages at medium height along cluttered edges. A South African report records it roosting in house and building roofs.
An extinction-risk assessment has not been added yet.